Timothy C Wang Selected Research

Metaplasia

1/2024	CDKN2A-p16 Deletion and Activated KRASG12D Drive Barrett's-Like Gland Hyperplasia-Metaplasia and Synergize in the Development of Dysplasia Precancer Lesions.
1/2023	SOX9 Modulates the Transformation of Gastric Stem Cells Through Biased Symmetric Cell Division.
1/2023	IL-1β transgenic mouse model of inflammation driven esophageal and oral squamous cell carcinoma.
9/2021	Epithelial memory of inflammation limits tissue damage while promoting pancreatic tumorigenesis.
1/2020	GPR30-Expressing Gastric Chief Cells Do Not Dedifferentiate But Are Eliminated via PDK-Dependent Cell Competition During Development of Metaplasia.
12/2019	Muc5ac null mice are predisposed to spontaneous gastric antro-pyloric hyperplasia and adenomas coupled with attenuated H. pylori-induced corpus mucous metaplasia.
1/2019	Evaluation of Lineage Changes in the Gastric Mucosa Following Infection With Helicobacter pylori and Specified Intestinal Flora in INS-GAS Mice.
1/2018	Mature gastric chief cells are not required for the development of metaplasia.
12/2016	Loss of Trefoil Factor 2 From Pancreatic Duct Glands Promotes Formation of Intraductal Papillary Mucinous Neoplasms in Mice.
2/2016	High-definition CpG methylation of novel genes in gastric carcinogenesis identified by next-generation sequencing.

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Timothy C Wang Research Topics

Disease

107	Neoplasms (Cancer) 04/2024 - 01/2002
56	Stomach Neoplasms (Stomach Cancer) 04/2024 - 10/2002
47	Carcinogenesis 04/2024 - 06/2005
34	Inflammation (Inflammations) 01/2024 - 02/2002
27	Metaplasia 01/2024 - 03/2003
26	Infections 03/2023 - 03/2003
23	Adenocarcinoma 12/2023 - 06/2003
13	Colorectal Neoplasms (Colorectal Cancer) 01/2023 - 09/2009
12	Hyperplasia 01/2024 - 02/2005
12	Gastritis 11/2023 - 08/2004
12	Barrett Esophagus (Barrett's Esophagus) 01/2023 - 05/2010
11	Atrophy 08/2011 - 11/2004
10	Colonic Neoplasms (Colon Cancer) 11/2021 - 11/2008
9	Pancreatic Neoplasms (Pancreatic Cancer) 11/2020 - 02/2009
7	Colitis 01/2023 - 01/2007
6	Chronic Pancreatitis 01/2018 - 10/2008
5	Carcinoma (Carcinomatosis) 12/2008 - 03/2003
4	Neoplasm Metastasis (Metastasis) 03/2024 - 09/2009
4	Esophageal Neoplasms (Esophageal Cancer) 01/2020 - 02/2013
4	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 07/2013 - 10/2004
4	Helicobacter Infections 06/2011 - 03/2003
3	Anemia 03/2023 - 01/2015
3	Ulcer 01/2021 - 11/2004
3	Celiac Disease (Celiac Sprue) 01/2021 - 01/2008
3	COVID-19 01/2021 - 01/2020
3	Myocardial Infarction 01/2018 - 08/2015
3	Peptic Ulcer (Peptic Ulcers) 12/2016 - 11/2004
2	Gastroesophageal Reflux (GERD) 12/2023 - 12/2016
2	Coinfection 11/2023 - 04/2014
2	Persistent Infection 03/2023 - 11/2004
2	Colitis-Associated Neoplasms 01/2023 - 02/2009
2	Adenoma (Adenomas) 11/2022 - 05/2003
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2022 - 01/2015

Drug/Important Bio-Agent (IBA)

37	GastrinsIBA 01/2021 - 01/2002
16	Proteins (Proteins, Gene)FDA Link 09/2022 - 06/2003
15	CytokinesIBA 01/2023 - 01/2002
15	Histamine (Histamine Dihydrochloride)FDA Link 01/2021 - 03/2004
13	AntralIBA 01/2022 - 02/2002
13	Messenger RNA (mRNA)IBA 12/2019 - 08/2003
11	Interleukin-6 (Interleukin 6)IBA 01/2023 - 02/2009
11	spasmolytic polypeptideIBA 01/2020 - 06/2003
11	big gastrinIBA 06/2017 - 05/2003
10	Peptides (Polypeptides)IBA 01/2022 - 06/2003
9	Histidine DecarboxylaseIBA 01/2022 - 10/2002
9	Cholecystokinin B ReceptorIBA 01/2021 - 08/2003
7	InterleukinsIBA 01/2024 - 02/2012
7	Biomarkers (Surrogate Marker)IBA 11/2023 - 02/2016
6	AzoxymethaneIBA 01/2023 - 09/2009
6	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 12/2008
6	EnzymesIBA 01/2020 - 03/2004
6	Trefoil FactorsIBA 12/2019 - 08/2003
6	Trefoil Factor-2IBA 12/2016 - 11/2006
5	Dextrans (Dextran)FDA Link 01/2023 - 01/2007
5	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2023 - 01/2007
5	LigandsIBA 01/2023 - 02/2013
5	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2021 - 10/2004
5	Conditioned Culture MediaIBA 01/2020 - 02/2012
5	CarcinogensIBA 12/2018 - 05/2003
5	AcidsIBA 01/2014 - 01/2002
5	Interleukin-1beta (Interleukin 1 beta)IBA 06/2011 - 01/2002
4	Transcription Factors (Transcription Factor)IBA 11/2023 - 10/2015
4	AntibodiesIBA 11/2022 - 06/2003
4	ChemokinesIBA 01/2022 - 03/2007
4	Tamoxifen FDA LinkGeneric 01/2022 - 09/2011
4	YF 476IBA 01/2021 - 06/2005
4	Proton Pump InhibitorsIBA 10/2015 - 05/2010
3	Mitogen-Activated Protein KinasesIBA 04/2024 - 02/2009
3	Bile Acids and Salts (Bile Acids)IBA 12/2023 - 01/2012
3	IronIBA 03/2023 - 01/2015
3	Phosphotransferases (Kinase)IBA 01/2021 - 08/2014
3	Interleukin-8 (Interleukin 8)IBA 01/2021 - 01/2013
3	Dextran SulfateIBA 01/2021 - 02/2011
3	Famotidine (Pepcid)FDA LinkGeneric 01/2021 - 01/2020
3	DMP 777IBA 01/2020 - 04/2006
3	Anti-Bacterial Agents (Antibiotics)IBA 01/2020 - 05/2008
3	MucinsIBA 12/2019 - 02/2009
3	Cyclin D1IBA 01/2019 - 07/2003
3	Cholinergic Agents (Cholinergics)IBA 11/2018 - 08/2014
3	Interleukin-17 (Interleukin 17)IBA 01/2018 - 03/2014
3	Hormones (Hormone)IBA 07/2013 - 12/2007
3	loxtidineIBA 01/2013 - 06/2005
3	Small Interfering RNA (siRNA)IBA 01/2012 - 05/2009
3	SaltsIBA 02/2011 - 03/2003
3	Insulin (Novolin)FDA Link 01/2011 - 10/2003
3	Histidine (L-Histidine)FDA Link 06/2006 - 03/2004
3	Glycine (Aminoacetic Acid)FDA LinkGeneric 04/2005 - 01/2004
2	Gastric MucinsIBA 04/2024 - 12/2016
2	LectinsIBA 04/2024 - 01/2019
2	Cadherins (E-Cadherin)IBA 12/2023 - 12/2015
2	Cytotoxins (Cytolysins)IBA 03/2023 - 11/2017
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2023 - 03/2010
2	RNA (Ribonucleic Acid)IBA 01/2023 - 11/2020
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2022 - 03/2014
2	CateninsIBA 01/2022 - 01/2019
2	LipopolysaccharidesIBA 01/2022 - 12/2017
2	Bromodeoxyuridine (BrdU)IBA 01/2022 - 05/2012

Therapy/Procedure

27	Therapeutics 01/2023 - 05/2003
5	Transplantation 02/2016 - 09/2009
3	Vagotomy 11/2018 - 08/2014
3	Denervation 02/2016 - 08/2014